Recombinant Human FABP3 Protein

SKU: PKSH030830

Size: 100μg

Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Exp date: 12 months

Category ID_II: Recombinant Proteins

Category ID_III: Others

Abbreviation:

Target Synonym: FABP11;FABP3;Fatty Acid-Binding Protein 3;Fatty Acid-Binding Protein Heart;H-FABP;Heart-Type Fatty Acid-Binding Protein;M-FABP;MDGI;MDGIMuscle Fatty Acid-Binding Protein;Mammary-Derived Growth Inhibitor;O-FABP

Research Areas: Signal Transduction;Cardiovascular;Cancer;metabolism

Conjugation:

Target Species: Human

Expression Host: E.coli

Application:

Fusion tag: None

UNIProt ID: P05413

Accession: P05413

Background: Fatty acid binding protein 3 (FABP3; also termed heart-type fatty acid binding protein) is a member of the intracellular lipid-binding protein family that may be essential in fatty acid transport; cell growth; cellular signaling and gene transcription. Previously FABP3 was involved in apoptosis-associated congenital cardiac malformations. FABP3 knockdown exhibited significant toxic effects on cardiac development and mitochondrial function; which may be responsible for the knockdown of FABP3-induced apoptosis. FABP3 as a candidate gene underlying the etiology of congenital heart defects. Overexpression of FABP3 inhibited cell growth and proliferation via negative regulation of the cell cycle and down-regulation of cell growth factors; but enhances cell survival in hypoxic or ischemic conditions. FABPs are known to be carrier proteins for transporting fatty acids and other lipophilic substances from the cytoplasm to the nucleus; where these lipids are released to a group of nuclear receptors such as peroxisome proliferator-activated receptors (PPARs).

Concentration:

Activity: Not validated for activity

Sequence: Met 1-Ala 133

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from sterile 50mM Tris, pH 8.0
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Reconstitution: Please refer to the printed manual for detailed information.

Endotoxin: Please contact us for more information.

Calculated MW: 14.9 kDa

ObservedMW: