Recombinant Human Eotaxin-3/CCL26 protein

SKU: CD01865

Size:5 ug

Background:CCL26 is novel CC family chemokine, also known as TARC (thymus and activation regulated chemokine). It is encoded by CCL26 gene, which is located on Chr.7 in humans, and ubiquitously expressed at low levels in various tissues including heart and ovary. CCL26 elicits its effects activity by binding to the cell surface chemokine receptor CCR3, and chemotactic for eosinophils and basophils.

Research_area:Immunology

Purity:> 97 % by SDS-PAGE and HPLC analyses.

Source:Escherichia coli.

Full product name:Recombinant Human Eotaxin-3/CCL26

Biological activity:Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human CCR3 transfected HEK293 cells is in a concentration range of .5-2. μg/ml.

Synonyms:Eotaxin-3/CCL26,IMAC; TSC-1; MIP-4a; SCYA26; MIP-4alpha, Human

Endotoxin:Less than 1 EU/μg of rHuEotaxin-3/CCL26 as determined by LAL method.

Storage:-20ºC

Sequence:TRGSDISKTC CFQYSHKPLP WTWVRSYEFT SNSCSQRAVI FTTKRGKKVC THPRKKWVQK YISLLKTPKQ L

uniprot accession:Q9Y258

Molecular weight:Approximately 8.4 kDa, a single non-glycosylated polypeptide chain containing 71 amino acid residues.

Formulation:

Reconstitution:Lyophilized from a .2 μm filtered concentrated solution in PBS, pH 7.4.