Recombinant Human DKK1 Protein(His Tag)

SKU: PDMH100216

Size:100μg

Storage:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping:This product is provided as lyophilized powder which is shipped with ice packs.

Exp date:12 months

Category ID_II:Recombinant Proteins

Category ID_III:Others

Abbreviation:DKK1

Target Synonym:Dickkopf 1;Dickkopf 1 homolog;Dickkopf 1 like;Dickkopf homolog 1;Dickkopf like protein 1;Dickkopf related protein 1;Dickkopf WNT signaling pathway inhibitor 1;Dickkopf-1;Dickkopf-related protein 1;DKK 1;Dkk-1;Dkk1;DKK1;hDkk 1;hDkk-1;SK

Research Areas:Immunology;Cardiovascular;Stem Cells;Developmental Biology

Conjugation:

Target Species:Human

Expression Host:Mammalian

Application:

Fusion tag:C-His

UNIProt ID:O94907

Accession:O94907

Background:This gene encodes a protein that is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma.

Concentration:

Activity:Not validated for activity

Sequence:Thr32-His266

Purity: > 90% as determined by reducing SDS-PAGE.

Formulation:Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.

Reconstitution:It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Endotoxin:< 1.0 EU/mg of the protein as determined by the LAL method.

Calculated MW:25.7 kDa

ObservedMW:40-45 kDa