Recombinant GluR-2 Monoclonal Antibody

SKU: AN301279L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:GluR-2

Target Synonym:GRIA;GLUR;GluA;HBGR;GluR-K;GRIA2;GLUR2;GLURB;GluA2;GluR-K2;HBGR2;AMPA 2;AMPA selective glutamate receptor 2;AMPA2;AMPA-selective glutamate receptor 2;GLUR 2;GLUR B;GluR K2;GluR-2;GluR-B;Glutamate receptor 2;Glutamate receptor ionotropic;Glutamate receptor ionotropic AMPA 2;GluR-2

Research Areas:Neuroscience

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:IHC

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:9B1

UNIProt ID:P42262

Accession:

Background:Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to a family of glutamate receptors that are sensitive to alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA), and function as ligand-activated cation channels. These channels are assembled from 4 related subunits, GRIA1-4. The subunit encoded by this gene (GRIA2) is subject to RNA editing (CAG->CGG; Q->R) within the second transmembrane domain, which is thought to render the channel impermeable to Ca(2+). Human and animal studies suggest that pre-mRNA editing is essential for brain function, and defective GRIA2 RNA editing at the Q/R site may be relevant to amyotrophic lateral sclerosis (ALS) etiology.

Concentration:0.2 mg/mL

Immunogen:Recombinant Human GluR-2 protein

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A

Dilution:IHC 1:200-1:1000

Calculated MW:

ObservedMW: