Recombinant FBXW7 Monoclonal Antibody

SKU: AN301521L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies;Recombinant Antibodies

Abbreviation:FBXW7

Target Synonym:FBX;CDC;FBXO;hCdc;FBW;SEL;FBXW7;AGO;CDC4;FBW6;FBW7;FBX30;FBXO30;FBXW6;SEL-10;SEL10;hAgo;hCdc4;Archipelago;Archipelago homolog;DKFZp686F23254;Drosophila;Drosophila);E3 ubiquitin protein ligase;F box and WD 40 domain protein 7;F box and WD 40 domain protein 7 (archipelago homolog;F box and WD repeat domain containing 7;F box protein FBW7;F box protein FBX30;F box protein SEL 10;F box protein SEL10;F-box and WD repeat domain containing 7;F-box and WD-40 domain-containing protein 7;F-box protein FBX30;F-box/WD repeat-containing protein 7;FLJ16457;homolog of;Homolog of C elegans sel 10;Homolog of C.elegans sel10;S.cerevisiae;SEL 10

Research Areas:Cell Biology;Cancer

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;

Application:IHC;IF

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:A220

UNIProt ID:Q969H0

Accession:

Background:Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes and binds phosphorylated sites/phosphodegrons within target proteins and thereafter bring them to the SCF complex for ubiquitination.

Concentration:1 mg/mL

Immunogen:Recombinant human FBXW7 fragment

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A purified

Dilution:IHC 1:100-1:1000;IF 1:50

Calculated MW:

ObservedMW: