Recombinant ERK5 Monoclonal Antibody

SKU: AN300829L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:ERK5

Target Synonym:BMK;MAPK;PRKM;ERK;MAPK7;BMK1;ERK4;ERK5;PRKM7;Big MAP kinase 1;BMK 1;BMK 1 kinase;BMK-1;BMK1 Kinase;EC 2.7.11.24;ERK 4;ERK 5;ERK-5;Extracellular signal regulated kinase 5;Extracellular signal-regulated kinase 5;MAP kinase 7;MAPK 7;Mitogen activated protein kinase 7;MITOGEN-ACTIVATED;Mitogen-activated protein kinase 7;MK07;OTTHUMP00000065906;OTTHUMP00000065907;PRKM 7;PROTEIN KINASE;ERK 5

Research Areas:Neuroscience;Signal Transduction

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:5B13

UNIProt ID:Q13164

Accession:

Background:The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is specifically activated by mitogen-activated protein kinase kinase 5 (MAP2K5/MEK5). It is involved in the downstream signaling processes of various receptor molecules including receptor type kinases, and G protein-coupled receptors. In response to extracelluar signals, this kinase translocates to cell nucleus, where it regulates gene expression by phosphorylating, and activating different transcription factors. Four alternatively spliced transcript variants of this gene encoding two distinct isoforms have been reported.

Concentration:0.2 mg/mL

Immunogen:Recombinant Human ERK5 protein

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A

Dilution:WB 1:2000-1:10000

Calculated MW:88 kDa

ObservedMW:115 kDa