Recombinant Dopamine beta Hydroxylase Monoclonal Antibody

SKU: AN301975L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies;Recombinant Antibodies

Abbreviation:Dopamine beta Hydroxylase

Target Synonym:OTTHUMP;DBH;DBM;Dopamine beta hydroxylase;Dopamine beta monooxygenase;Dopamine beta-hydroxylase (dopamine beta-monooxygenase);Dopamine beta-monooxygenase;DOPO;OTTHUMP00000022501;Soluble dopamine beta-hydroxylase;dopamine beta-hydroxylase;Dopamine β-hydroxylase

Research Areas:Neuroscience;Cancer;Metabolism

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;

Application:IHC

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:A691

UNIProt ID:P09172

Accession:

Background:Dopamine β-Hydroxylase (DBH) is an enzyme of the copper type II ascorbate-dependent mono-oxygenase family. This enzyme forms homotetramers composed of two noncovalently bound disulfide-linked dimers and is found as both membrane-associated and soluble forms. The soluble form is present in the lumen of secretory granules and is released from cells by exocytosis. DBH converts dopamine to noradrenaline. Deficiency in this enzyme causes a rare disease characterized by a complete absence of noradrenaline and adrenaline in plasma together with increased plasma dopamine levels. Orthostatic hypotension, the main symptom of DBH deficiency, can be alleviated by administration of dihydroxyphenylserine, a synthetic precursor of noradrenaline.

Concentration:1 mg/mL

Immunogen:Peptide. This information is proprietary to PTMab.

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A purified

Dilution:IHC 1:50-1:100

Calculated MW:

ObservedMW: