Recombinant Cynomolgus CD3D&CD3E Heterodimer (C-Fc-Flag&C-Fc-6His)

SKU: PKSQ050124

Size: 50μg

Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Exp date: 12 months

Category ID_II: Recombinant Proteins

Category ID_III: Others

Abbreviation: CD3D&CD3E

Target Synonym: CD3 delta & CD3 epsilon;CD3 delta / epsilon;CD3E & CD3D

Research Areas:

Conjugation:

Target Species: Cynomolgus macaques

Expression Host: HEK293 Cells

Application:

Fusion tag: C-Fc-Flag & C-Fc-His

UNIProt ID: Q95LI8;Q95LI5

Accession: Q95LI8&Q95LI5

Background: T-cell surface glycoprotein CD3D & CD3E, also known as CD3 delta & CD3 epsilon chain, are single-pass type I membrane proteins. CD3D, together with CD3- epsilon(CD3E) , CD3-gamma and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. T cell receptor-CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways.

Concentration:

Activity: Not validated for activity

Sequence: Phe22-Ala105&Gln22-Asp117

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Reconstitution: Please refer to the printed manual for detailed information.

Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.

Calculated MW: 37&38.3 kDa

ObservedMW: 40-60 kDa