Recombinant CD40 Monoclonal Antibody

SKU: AN301709L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies;Recombinant Antibodies

Abbreviation:CD40

Target Synonym:CDW;B-cell surface antigen CD;Tumor necrosis factor receptor superfamily member;TNFRSF;CD40;Bp50;CDW40;TNFRSF5;p50;Tumor necrosis factor receptor superfamily member 5;B-cell surface antigen CD40;CD40L receptor;TNFRSF5;AI326936;B cell associated molecule CD40;B cell surface antigen CD40;B cell-associated molecule;CD 40;CD40 (protein);CD40 antigen;CD40 antigen (TNF receptor superfamily member 5);CD40 molecule;CD40 protein;CD40 type II isoform;GP39;HIGM1;IGM;IMD3;isoform CRA_a;member 5;MGC9013;Nerve growth factor receptor related B lymphocyte activation molecule;OTTHUMP00000031699;OTTHUMP00000031700;TBAM;T-BAM;TNF receptor superfamily member 5;TNR5;TRAP;Tumor necrosis factor receptor superfamily;Tumor necrosis factor receptor superfamily member 5 precursor

Research Areas:Immunology;Cardiovascular;Stem Cells

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;

Application:WB;IHC

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:A417

UNIProt ID:P25942

Accession:

Background:The CD40 antigen is a 44-48 kDa type I integral membrane protein of the tumor necrosis factor receptor (TNFR) superfamily. This antigen is found on B cell lines, is strongly expressed by interdigitating cells (IDC), basal epithelial cells, and is also present on macrophages, some endothelial cells, and follicular dendritic cells. It is a well-known regulator of T cell immunity including in cancer. CD40-ligand, primarily expressed on activated T cells, interacts with CD40 on APCs resulting in a ‘licensed’ state.

Concentration:1 mg/mL

Immunogen:Recombinant human CD40 fragment

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A purified

Dilution:WB 1:1000-1:5000;IHC 1:200-1:1000

Calculated MW:32 kDa

ObservedMW:44-48 kDa