Recombinant Caspase-14/CASP14 Monoclonal Antibody

SKU: AN300033P

Size::

Storage:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies

Abbreviation:CASP14

Target Synonym:ARCI;Caspase;CASP14;ARCI12;CASP-14;Caspase-14;MGC119078;MGC119079

Research Areas:Cell Biology

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human

Application:IHC-P;ICC/IF

Isotype:IgG

Clonality:Rabbit Monoclonal

Clone NO.:8D5

UNIProt ID:P31944

Accession:

Background:This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This caspase has been shown to be processed and activated by caspase 8 and caspase 7 in vitro, and by anti-Fas agonist antibody or TNF-related apoptosis inducing ligand in vivo. The expression and processing of this caspase may be involved in keratinocyte terminal differentiation, which is important for the formation of the skin barrier.

Concentration:1 mg/mL

Immunogen:Recombinant Human Caspase-14 / CASP14 protein

Buffer:0.2 μm filtered solution in PBS

Purification method:Protein A

Dilution:IHC-P 1:100-1:500;ICC/IF 1:20-1:100;

Calculated MW:

ObservedMW: