Recombinant Carbonic Anhydrase XIV/CA14 Monoclonal Antibody

SKU: AN300091P

Size::

Storage:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies

Abbreviation:CA14

Target Synonym:UNQ;PRO;CAH;UNQ690/PRO;CA 14;CA XIV;CAH14;Carbonate dehydratase XIV;Carbonic anhydrase 14;Carbonic anhydrase XIV;Carbonic dehydratase;CAXIV;CA-XIV;UNQ690/PRO1335;CA14;UNQ690;PRO1335

Research Areas:Neuroscience

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human

Application:IHC-P;ICC/IF

Isotype:IgG

Clonality:Rabbit Monoclonal

Clone NO.:6H2

UNIProt ID:Q9ULX7

Accession:

Background:The carbonic anhydrases (or carbonate dehydratases) are classified as metalloenzyme for its zinc ion prosthetic group and form a family of enzymes that catalyze the rapid interconversion of carbon dioxide and water to bicarbonate and protons, a reversible reaction that takes part in maintaining acid-base balance in blood and other tissues. The carbonic anhydrasekl (CA) family consists of at least 11 enzymatically active members and a few inactive homologous proteins. CAXIV is a member of CA family that showed an overall similarity of 29–46% to other active CA isozymes. The highest percentage similarity was with a transmembrane CA isoform, CAXII. The CAXIV was found high concentrations in human heart, brain, liver, and skeletal muscle but lower in the colon, small intestine, urinary bladder, and kidney. No CAXIV mRNA was seen in the salivary gland and pancreas. CAXIV is a likely candidate for the extracellular CA postulated to have an important role in modulating excitatory synaptic transmission in brain.

Concentration:1 mg/mL

Immunogen:Recombinant Human Carbonic Anhydrase XIV / CA14 Protein

Buffer:0.2 μm filtered solution in PBS

Purification method:Protein A

Dilution:IHC-P 1:100-1:500;ICC/IF 1:20-1:100;

Calculated MW:

ObservedMW: