Recombinant BTK Monoclonal Antibody

SKU: AN300703L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:Btk

Target Synonym:IMD;AGMX;PSCTK;AGMX1;AT;ATK;BPK;IMD1;PSCTK1;XLA;BTK;Bruton tyrosine kinase;AGMX1;ATK;BPK;Bruton tyrosine kinase;IMD1;PSCTK1;XLA

Research Areas:Signal Transduction;Immunology

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human

Application:WB

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:11D12

UNIProt ID:Q06187

Accession:

Background:The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms.

Concentration:0.2 mg/mL

Immunogen:Recombinant Human BTK protein

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A

Dilution:WB 1:2000-1:10000

Calculated MW:67 kDa

ObservedMW:67 kDa