Recombinant Alpha B Crystallin Monoclonal Antibody

SKU: AN301434L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies;Recombinant Antibodies

Abbreviation:Alpha B Crystallin

Target Synonym:MFM;CRYA;CTPP;HSPB;Heat Shock Protein Beta;Renal Carcinoma Antigen NY-REN;CTRCT;HEL-S;CRYAB;CMD1II;CRYA2;CTPP2;CTRCT16;HEL-S-101;HSPB5;MFM2;Alpha(B)-Crystallin;Alpha-Crystallin B Chain;Heat Shock Protein Beta-5;Renal Carcinoma Antigen NY-REN-27;Rosenthal Fiber Component;AACRYA;Alpha B crystallin;Alpha crystallin B chain;Crystallin alpha B;Crystallin alpha polypeptide 2;Heat shock 20 kD like protein;Heat shock protein beta 5;Renal carcinoma antigen NY REN 27

Research Areas:Signal Transduction;Neuroscience;Cancer;Metabolism

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Rat;Mouse

Application:WB;IHC

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:A129

UNIProt ID:P02511

Accession:

Background:Mammalian lens crystallins are divided into alpha, beta, and gamma families. Alpha crystallins are composed of two gene products: alpha-A and alpha-B, for acidic and basic, respectively. Alpha crystallins can be induced by heat shock and are members of the small heat shock protein (HSP20) family. They act as molecular chaperones although they do not renature proteins and release them in the fashion of a true chaperone; instead they hold them in large soluble aggregates. These heterogeneous aggregates consist of 30-40 subunits; the alpha-A and alpha-B subunits have a 3:1 ratio, respectively. Two additional functions of alpha crystallins are an autokinase activity and participation in the intracellular architecture.

Concentration:1 mg/mL

Immunogen:Recombinant human Alpha B Crystallin fragment

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A purified

Dilution:WB 1:500-1:2000;IHC 1:200-1:1000

Calculated MW:20 kDa

ObservedMW:22 kDa