Recombinant alpha Actinin 4 Monoclonal Antibody

SKU: AN301433L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies;Recombinant Antibodies

Abbreviation:alpha Actinin 4

Target Synonym:ACTN;Non-muscle alpha-actinin;ACTININ;ACTN4;ACTININ-4;FSGS;FSGS1;Non-muscle alpha-actinin 4;actinin 4;Actinin alpha 4;actinin4;ACTN 4;Alpha-actinin-4;DKFZp686K23158;F actin cross linking protein;F-actin cross-linking protein;Focal segmental glomerulosclerosis 1;FSGS 1;Non muscle alpha actinin 4

Research Areas:Signal Transduction;Cancer;Metabolism

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse

Application:WB;IHC;IF

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:A128

UNIProt ID:O43707

Accession:

Background:F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein. Probably involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation. Involved in tight junction assembly in epithelial cells probably through interaction with MICALL2. Links MICALL2 to the actin cytoskeleton and recruits it to the tight junctions. May also function as a transcriptional coactivator, stimulating transcription mediated by the nuclear hormone receptors PPARG and RARA.

Concentration:1 mg/mL

Immunogen:Recombinant human Actinin 4 fragment

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A purified

Dilution:WB 1:500-1:1000;IHC 1:50-1:100;IF 1:50-1:100

Calculated MW:100 kDa

ObservedMW:110 kDa