Recombinant Actinin-α2 Monoclonal Antibody

SKU: AN300596L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:Actinin-α2

Target Synonym:CMH;ACTN;ACTN2;CMD1AA;CMH23;Actin binding protein;actinin alpha 2;ACTN 2;Alpha actinin 2;Alpha actinin skeletal muscle;Alpha actinin skeletal muscle isoform 2;Alpha-actinin skeletal muscle isoform 2;Alpha-actinin-2;F actin cross linking protein;F-actin cross-linking protein;Actinin α2

Research Areas:Signal Transduction;Cardiovascular

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:1A6

UNIProt ID:P35609

Accession:

Background:Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles. Several transcript variants encoding different isoforms have been found for this gene.

Concentration:0.2 mg/mL

Immunogen:Recombinant Human Actinin-α2 protein

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A

Dilution:WB 1:500-1:2000

Calculated MW:104 kDa

ObservedMW:104 kDa