Recombinant Aconitase 1/ACO1 Monoclonal Antibody

SKU: AN301871L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies;Recombinant Antibodies

Abbreviation:Aconitase 1/ACO1

Target Synonym:HEL;IRP;ACO;IREB;ACO1;ACONS;HEL60;IREB1;IREBP;IREBP1;IRP1;ACO 1;ACOC;Aconitase;Aconitase 1 soluble;Aconitase1;Aconitate hydratase;Citrate hydro lyase;Citrate hydro-lyase;Cytoplasmic aconitate hydratase;Ferritin repressor protein;IRE BP 1;IREB 1;IRE-BP 1;Iron regulatory protein 1;Iron responsive element binding protein 1;Iron-responsive element-binding protein 1;IRP 1;OTTHUMP00000045233

Research Areas:Cardiovascular;Signal Transduction;Epigenetics and Nuclear Signaling;Metabolism

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Rat;Mouse

Application:WB

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:A583

UNIProt ID:P21399

Accession:

Background:Aconitase 1 is a bifunctional, cytosolic protein that functions as an essential enzyme in the TCA cycle and interacts with mRNA to control the levels of iron inside cells. When cellular iron levels are high, this protein binds to a 4Fe-4S cluster and functions as an aconitase. Aconitases are iron-sulfur proteins that function to catalyze the conversion of citrate to isocitrate. When cellular iron levels are low, the protein binds to iron-responsive elements (IREs), which are stem-loop structures found in the 5' UTR of ferritin mRNA, and in the 3' UTR of transferrin receptor mRNA.

Concentration:1 mg/mL

Immunogen:Recombinant human Aconitase 1/ACO1 fragment

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A purified

Dilution:WB 1:500-1:2000

Calculated MW:98 kDa

ObservedMW:105 kDa