RBP3 Polyclonal Antibody

SKU: E-AB-40147

Size: 100μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: RBP3

Target Synonym: D10S64;D10S65;D10S66;Interphotoreceptor retinoid binding protein;Interphotoreceptor retinoid-binding protein;Interstitial retinol binding protein;Interstitial retinol-binding protein;IRBP;RBP 3;rbp3;RBPI;RET3;Retinol binding protein 3;Retinol binding protein 3 interstitial;Retinol-binding protein 3;RP66

Research Areas: Neuroscience

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Mouse;Rat

Application: IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: P10745

Accession:

Background: Interphotoreceptor retinol-binding protein is a large glycoprotein known to bind retinoids and found primarily in the interphotoreceptor matrix of the retina between the retinal pigment epithelium and the photoreceptor cells. It is thought to transport retinoids between the retinal pigment epithelium and the photoreceptors, a critical role in the visual process.The human IRBP gene is approximately 9.5 kbp in length and consists of four exons separated by three introns. The introns are 1.6-1.9 kbp long. The gene is transcribed by photoreceptor and retinoblastoma cells into an approximately 4.3-kilobase mRNA that is translated and processed into a glycosylated protein of 135,000 Da. The amino acid sequence of human IRBP can be divided into four contiguous homology domains with 33-38% identity, suggesting a series of gene duplication events. In the gene, the boundaries of these domains are not defined by exon-intron junctions, as might have been expected. The first three homology domains and part of the fourth are all encoded by the first large exon, which is 3,180 base pairs long. The remainder of the fourth domain is encoded in the last three exons, which are 191, 143, and approximately 740 base pairs long, respectively.

Concentration: 1 mg/mL

Immunogen: Recombinant Human Retinol-binding protein 3 protein

Buffer: PBS with 0.02% sodium azide,1% protective protein and 50% glycerol,pH7.4

Purification method: Antigen Affinity Purification

Dilution: IHC 1:50-1:100

Calculated MW:

ObservedMW: