RBM5 Antibody - Cat. #: CSB-PA239401

SKU: CSB-PA239401

Size :100ul

Clone Number:

Aliases:FLJ39876 antibody; G15 antibody; H37 antibody; LUCA 15 antibody; LUCA15 antibody; Protein G15 antibody; Putative tumor suppressor LUCA15 antibody; RBM 5 antibody; Rbm5 antibody; RBM5_HUMAN antibody; Renal carcinoma antigen NY REN 9 antibody; Renal carcinoma antigen NY-REN-9 antibody; RMB 5 antibody; RMB5 antibody; RNA binding motif protein 5 antibody; RNA binding protein 5 antibody; RNA-binding motif protein 5 antibody; RNA-binding protein 5 antibody; Tumor suppressor LUCA15 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P52756

Immunogen:Synthesized peptide derived from internal of Human RBM5.

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, WB, IHC; WB:1:500-1:3000, IHC:1:50-1:100

Background:Component of the spliceosome A complex. Regulates alternative splicing of a number of mRNAs. May modulate splice site pairing after recruitment of the U1 and U2 snRNPs to the 5' and 3' splice sites of the intron. May both positively and negatively regulate aopotosis by regulating the alternative splicing of several genes involved in this process, including FAS and CASP2/caspase-2. In the case of FAS, promotes exclusion of exon 6 thereby producing a soluble form of FAS that inhibits apoptosis. In the case of CASP2/caspase-2, promotes exclusion of exon 9 thereby producing a catalytically active form of CASP2/Caspase-2 that induces apoptosis.

Bader S., Submitted (APR-1996) to the EMBL/GenBank/DDBJ databases.
Timmer T., Genomics 60:238-240(1999).
Oh J.J., Nucleic Acids Res. 27:4008-4017(1999).

Clonality:Polyclonal

Isotype:IgG

Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:RBM5

Research Areas:Epigenetics and Nuclear Signaling;Cancer