RBM38 Antibody - Cat. #: CSB-PA880939LA01HU

SKU: CSB-PA880939LA01HU

Size :50ug

Clone Number:

Aliases:CLL associated antigen KW 5 antibody; CLL-associated antigen KW-5 antibody; HSRNASEB antibody; RBM38 antibody; RBM38_HUMAN antibody; RNA binding motif protein 38 antibody; RNA binding protein 38 antibody; RNA binding region (RNP1; RRM) containing 1 antibody; RNA binding region containing protein 1 antibody; RNA-binding motif protein 38 antibody; RNA-binding protein 38 antibody; RNA-binding region-containing protein 1 antibody; RNPC1 antibody; SEB4 antibody; SEB4B antibody; SEB4D antibody; ssDNA binding protein SEB4 antibody; ssDNA-binding protein SEB4 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9H0Z9

Immunogen:Recombinant Human RNA-binding protein 38 protein (1-239AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200

Background:RNA-binding protein that specifically bind the 3\'-UTR of CDKN1A transcripts, leading to maintain the stability of CDKN1A transcripts, thereby acting as a mediator of the p53/TP53 family to regulate CDKN1A. CDKN1A is a cyclin-dependent kinase inhibitor transcriptionally regulated by the p53/TP53 family to induce cell cycle arrest. Isoform 1, but not isoform 2, has the ability to induce cell cycle arrest in G1 and maintain the stability of CDKN1A transcripts induced by p53/TP53. Also acts as a mRNA splicing factor. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Plays a role in myogenic differentiation.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Non-conjugated

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:RBM38

Research Areas:Epigenetics and Nuclear Signaling; Cell biology; Developmental biology; Stem cells