Rat Steroid 21-hydroxylase, CYP21A2 ELISA Kit

SKU: E1500Ra

Size:96 Tests-1 Kit

Background:A cytochrome P450 monooxygenase that plays a major role in adrenal steroidogenesis. Catalyzes the hydroxylation at C-21 of progesterone and 17alpha-hydroxyprogesterone to respectively form 11-deoxycorticosterone and 11-deoxycortisol, intermediate metabolites in the biosynthetic pathway of mineralocorticoids and glucocorticoids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase).

Research_area:Cardiovascular

Applications:ELISA

Target_protein:CYP21A2

Reactivity:Rat

Assay type:Sandwich

Sensitivity:10.31ng/L

Detection range:20-6000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Steroid 21-hydroxylase

Species:Rat

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q64562

MASS(Da):55,946

GeneID:24298

Synonyms:21-OH;21-OHase;Cyp21;CYP21A2;Cytochrome P450 21;Cytochrome P450 XXI;Cytochrome P450-C21;Cytochrome P-450c21;Steroid 21-hydroxylase;

Gene names:Cyp21

Standard solution:6400ng/L