Rat SPRY domain-containing SOCS box protein 2,SPSB2 ELISA KIT

SKU: E0976Ra

Size:96 Tests-1 Kit

Background:Substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). Negatively regulates nitric oxide (NO) production and limits cellular toxicity in activated macrophages by mediating the ubiquitination and proteasomal degradation of NOS2 (By similarity). Acts as a bridge which links NOS2 with the ECS E3 ubiquitin ligase complex components ELOC and CUL5 (By similarity). {ECO:0000250|UniProtKB:Q99619}.

Research_area:

Applications:ELISA

Target_protein:Spsb2

Reactivity:Rat

Assay type:Sandwich

Sensitivity:0.1ng/ml

Detection range:0.19-12ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:SPRY domain-containing SOCS box protein 2

Species:Rat

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q5M877

MASS(Da):28797

GeneID:297592

Synonyms:Spsb2 Ssb2

Gene names:Spsb2

Standard solution:24ng/ml