Rat Protein Tyrosine Phosphatase Non Receptor Type 11,PTPN11 ELISA KIT

SKU: E0813Ra

Size:96 Tests-1 Kit

Background:Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus (By similarity). Positively regulates MAPK signal transduction pathway. Dephosphorylates GAB1, ARHGAP35 and EGFR. Dephosphorylates ROCK2 at 'Tyr-722' resulting in stimulation of its RhoA binding activity. Dephosphorylates CDC73 (By similarity). Dephosphorylates SOX9 on tyrosine residues, leading to inactivate SOX9 and promote ossification (By similarity). {ECO:0000250|UniProtKB:P35235, ECO:0000250|UniProtKB:Q06124}.

Research_area:

Applications:ELISA

Target_protein:Ptpn11

Reactivity:Rat

Assay type:Sandwich

Sensitivity:12.21ng/L

Detection range:30-9000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Protein Tyrosine Phosphatase Non Receptor Type 11

Species:Rat

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P41499

MASS(Da):68033

GeneID:25622

Synonyms:Ptpn11

Gene names:Ptpn11

Standard solution:9600ng/L