Rat Klotho, KL ELISA Kit

SKU: E1206Ra

Size:96 Tests-1 Kit

Background:May have weak glycosidase activity towards glucuronylated steroids. However, it lacks essential active site Glu residues at positions 241 and 874, suggesting it may be inactive as a glycosidase in vivo. May be involved in the regulation of calcium and phosphorus homeostasis by inhibiting the synthesis of active vitamin D (By similarity). Essential factor for the specific interaction between FGF23 and FGFR1 (By similarity). The Klotho Peptide generated by cleavage of the membrane-bound isoform may be an anti-aging circulating hormone which would extend life span by inhibiting insulin/IGF1 signaling.

Research_area:Developmental Biology

Applications:ELISA

Target_protein:KL

Reactivity:Rat

Assay type:Sandwich

Sensitivity:0.02ng/ml

Detection range:0.04-20ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Klotho

Species:Rat

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q9Z2Y9

MASS(Da):116,800

GeneID:83504

Synonyms:KL;Klotho;Klotho Peptide

Gene names:KL

Standard solution:24ng/ml