Rat Glutamate Oxaloacetate Transaminase 1, GOT1 ELISA Kit

SKU: E1141Ra

Size:96 Tests-1 Kit

Background:Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-mercaptopyruvate sulfurtransferase (3MST). Hydrogen sulfide is an important synaptic modulator and neuroprotectant in the brain.

Research_area:Signal Transduction

Applications:ELISA

Target_protein:GOT1

Reactivity:Rat

Assay type:Sandwich

Sensitivity:1.07U/L

Detection range:2-600U/L

Sample type:Serum, plasma or other biological fluids

Full product name:Glutamate Oxaloacetate Transaminase 1

Species:Rat

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P13221

MASS(Da):46,429

GeneID:24401

Synonyms:Aspartate aminotransferase, cytoplasmic;cAspAT;cCAT;Cysteine aminotransferase, cytoplasmic;Cysteine transaminase, cytoplasmic;Glutamate oxaloacetate transaminase 1;GOT 1;GOT1;Transaminase A;

Gene names:GOT1

Standard solution:800U/L