Rat Endothelin 1/EDN1 ELISA Kit PicoKine®

SKU: EK0952

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Rat

Applications: ELISA

Application Details:

Gene Name: EDN1

Specificity: Natural and recombinant rat Endothelin

Background: The endothelins is a family of structurally and pharmacologically distinct peptides, which has been identified and sequenced in humans. Three isoforms of human endothelin have been identified: endothelin-1, -2, and -3. Endothelin-1 is a potent, 21-amino acid vasoconstrictor peptide produced by vascular endothelial cells. Endothelins are 21-amino acid vasoconstricting peptides produced primarily in the endothelium having a key role in vascular homeostasis. Endothelins are implicated in vascular diseases of several organ systems, including the heart, general circulation and brain. Endothelins are proteins that constrict blood vessels and raise blood pressure. They are normally kept in balance by other mechanisms, but when they are over-expressed, they contribute to high blood pressure (hypertension) and heart disease.

Immunogen: A peptide reflecting the target protein in human. Sequence: C53-W73

Clonality:

Contents:

Purification:

Reconstitution:

Reference:

Uniprot ID: P22388

Host:

Concentration:

Conjugate:

Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

Isotype:

Phospho_site:

Clone Number:

Observed Molecular Weight:

Calculated Molecular Weight:

Gene ID: 24323

Protein Name: Endothelin-1

Gene Full Name: endothelin 1

Synonyms: Big endothelin 1; ET1; HDLCQ7; PPET1; Preproendothelin 1; EDN2; EDN2_HUMAN; Endothelin 2; Endothelin-2; ET 2; ET-2; ET2; PPET2; Preproendothelin 2; Preproendothelin-2; EDN3; EDN3_HUMAN; Endothelin-3; ET 3; ET-3; PPET3; Preproendothelin 3; Preproendothelin-3