Rat Bone Morphogenetic Protein 10, BMP-10 ELISA Kit

SKU: E1699Ra

Size:96 Tests-1 Kit

Background:Required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. Acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors. Inhibits endothelial cell migration and growth. May reduce cell migration and cell matrix adhesion in breast cancer cell lines.

Research_area:Signal Transduction; Cardiovascular

Applications:ELISA

Target_protein:BMP10

Reactivity:Rat

Assay type:Sandwich

Sensitivity:0.52ng/L

Detection range:1.03-300ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Bone Morphogenetic Protein 10

Species:Rat

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q4AEG6

MASS(Da):47,767

GeneID:500245

Synonyms:BMP 10;BMP10;BMP-10;Bone morphogenetic protein 10

Gene names:BMP10

Standard solution:320ng/L