Rat Arginase-2, ARG2 ELISA Kit

SKU: E1872Ra

Size:96 Tests-1 Kit

Background:May play a role in the regulation of extra-urea cycle arginine metabolism and also in down-regulation of nitric oxide synthesis. Extrahepatic arginase functions to regulate L-arginine bioavailability to nitric oxid Synthase (NOS). Arginine metabolism is a critical regulator of innate and adaptive immune responses. Seems to be involved in negative regulation of the survival capacity of activated T cells. May suppress inflammation-related signaling in asthmatic airway epithelium. May play a role in promoting prenatal immune suppression. Regulates RPS6KB1 signaling, which promotes endothelial cell senescence and inflammation and implicates NOS3/eNOS dysfunction. Can inhibit endothelial autophagy independently of its enzymatic activity implicating mTORC2 signaling. Involved in vascular smooth muscle cell senescence and apoptosis independently of its enzymatic activity.

Research_area:Signal Transduction

Applications:ELISA

Target_protein:ARG2

Reactivity:Rat

Assay type:Sandwich

Sensitivity:0.152ng/mL

Detection range:0.3-90ng/mL

Sample type:Serum, plasma or other biological fluids

Full product name:Arginase-2

Species:Rat

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:O08701

MASS(Da):38,640

GeneID:29215

Synonyms:ARG 2;ARG2;Arginase II;Arginase-2, mitochondrial;Kidney-type arginase;Non-hepatic arginase;Type II arginase

Gene names:ARG2

Standard solution:96ng/mL