Rat Aquaporin 3, AQP-3 ELISA Kit

SKU: E0567Ra

Size:96 Tests-1 Kit

Background:Aquaporin 3 is the protein product of the human AQP3 gene. It is found in the basolateral cell membrane of principal collecting duct cells and provides a pathway for water to exit these cells. Aquaporin 3 is also permeable to glycerol, ammonia, urea, and hydrogen peroxide. It is expressed in various tissues including the skin, respiratory tract, and kidneys as well as various types of cancers. In the kidney, aquaproin 3 is unresponsive to vasopressin (a.k.a. Antidiuretic Hormone), unlike Aquaporin 2. This protein is also a determinant for the GIL blood group system. Suberoylanilide hydroxamic acid (SAHA) (a HDAC inhibitor) increases expression of aquaporin-3 in normal skin cells (keratinocytes).

Research_area:Signal Transduction

Applications:ELISA

Target_protein:AQP-3

Reactivity:Rat

Assay type:Sandwich

Sensitivity:13.92ng/L

Detection range:20-7000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Aquaporin 3

Species:Rat

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P47862

MASS(Da):31,384

GeneID:65133

Synonyms:31.4 kDa water Channel protein;AQP-3;Aquaglyceroporin-3;Aquaporin-3

Gene names:Aqp3

Standard solution:8000ng/L