Rat Angiotensin Converting Enzyme 2, ACE2 ELISA Kit

SKU: E0968Ra

Size:96 Tests-1 Kit

Background:Essential counter-regulatory carboxypeptidase of the renin-angiotensin hormone system that is a critical regulator of blood volume, systemic vascular resistance, and thus cardiovascular homeostasis. Converts angiotensin I to angiotensin 1-9, a nine-amino acid Peptide with anti-hypertrophic effects in cardiomyocytes, and angiotensin II to angiotensin 1-7, which then acts as a beneficial vasodilator and anti-proliferation agent, counterbalancing the actions of the vasoconstrictor angiotensin II. Also removes the C-terminal residue from three other vasoactive Peptides, neurotensin, kinetensin, and des-Arg bradykinin, but is not active on bradykinin. Also cleaves other biological Peptides, such as apelins, casomorphins and dynorphin A. Plays an important role in amino acid transport by acting as binding partner of amino acid transporter SLC6A19 in intestine, regulating trafficking, expression on the cell surface, and its catalytic activity.

Research_area:Microbiology; Cell Biology; Cardiovascular

Applications:ELISA

Target_protein:ACE2

Reactivity:Rat

Assay type:Sandwich

Sensitivity:0.23ng/ml

Detection range:0.5-100ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Angiotensin Converting Enzyme 2

Species:Rat

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q5EGZ1

MASS(Da):92,491

GeneID:302668

Synonyms:ACE 2;ACE2;ACE-related carboxypeptidase;Angiotensin-converting enzyme 2;Processed angiotensin-converting enzyme 2

Gene names:ACE2

Standard solution:128ng/ml