Rat Aldehyde oxidase,Aox1 ELISA KIT

SKU: E2895Ra

Size:96 Tests-1 Kit

Background:Oxidase with broad substrate specificity, oxidizing aromatic azaheterocycles, such as N1-methylnicotinamide, N-methylphthalazinium and phthalazine, as well as aldehydes, such as benzaldehyde, retinal, pyridoxal, and vanillin. Plays a role in the metabolism of xenobiotics and drugs containing aromatic azaheterocyclic substituents. Participates in the bioactivation of prodrugs such as famciclovir, catalyzing the oxidation step from 6-deoxypenciclovir to penciclovir, which is a potent antiviral agent. Is probably involved in the regulation of reactive oxygen species homeostasis. Is a prominent source of superoxide generation via the one-electron reduction of molecular oxygen. Also catalyzes nitric oxide (NO) production; under anaerobic conditions, reduces nitrite to NO with NADH or aldehyde as electron donor, but under aerobic conditions, NADH is the preferred substrate. These reactions may be catalyzed by several isozymes. May play a role in adipogenesis. {ECO:0000269|PubMed:17353002, ECO:0000269|PubMed:19801639, ECO:0000269|PubMed:23282065, ECO:0000269|PubMed:9224775, ECO:0000269|PubMed:9920943}.

Research_area:

Applications:ELISA

Target_protein:Aox1

Reactivity:Rat

Assay type:Sandwich

Sensitivity:0.27ng/ml

Detection range:0.5-150ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Aldehyde oxidase

Species:Rat

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q9Z0U5

MASS(Da):146921

GeneID:54349

Synonyms:Aox1 Ao

Gene names:Aox1

Standard solution:160ng/ml