Rat adenosine deaminase,ADA ELISA KIT

SKU: E6280Ra

Size:96 Tests-1 Kit

Background:Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine. Plays an important role in purine metabolism and in adenosine homeostasis. Modulates signaling by extracellular adenosine, and so contributes indirectly to cellular signaling events. Acts as a positive regulator of T-cell coactivation, by binding DPP4. Its interaction with DPP4 regulates lymphocyte-epithelial cell adhesion. Enhances dendritic cell immunogenicity by affecting dendritic cell costimulatory molecule expression and cytokines and chemokines secretion. Enhances CD4+ T-cell differentiation and proliferation. Acts as a positive modulator of adenosine receptors ADORA1 and ADORA2A, by enhancing their ligand affinity via conformational change. Stimulates plasminogen activation. Plays a role in male fertility. Plays a protective role in early postimplantation embryonic development. {ECO:0000250|UniProtKB:P00813, ECO:0000250|UniProtKB:P03958, ECO:0000250|UniProtKB:P56658}.

Research_area:

Applications:ELISA

Target_protein:Ada

Reactivity:Rat

Assay type:Sandwich

Sensitivity:40.4ng/L

Detection range:100-6400ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:

Species:Rat

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q920P6

MASS(Da):39899

GeneID:24165

Synonyms:Ada

Gene names:Ada

Standard solution:12800ng/L