Rat 5-Hydroxytryptamine Receptor 1B,HTR1B ELISA KIT

SKU: E2863Ra

Size:96 Tests-1 Kit

Background:G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various alkaloids and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. Arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Regulates the release of 5-hydroxytryptamine, dopamine and acetylcholine in the brain, and thereby affects neural activity, nociceptive processing, pain perception, mood and behavior. Besides, plays a role in vasoconstriction of cerebral arteries. {ECO:0000269|PubMed:1836757, ECO:0000269|Ref.1}.

Research_area:

Applications:ELISA

Target_protein:Htr1b

Reactivity:Rat

Assay type:Sandwich

Sensitivity:10.66ng/L

Detection range:20-4500ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:5-Hydroxytryptamine Receptor 1B

Species:Rat

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P28564

MASS(Da):43163

GeneID:25075

Synonyms:Htr1b 5ht1b

Gene names:Htr1b

Standard solution:4800ng/L