RASGEF1A Antibody - Cat. #: CSB-PA829156

SKU: CSB-PA829156

Size :50ul

Clone Number:

Aliases:CG4853 gene product antibody; Ras-GEF domain-containing family member 1A antibody; RasGEF domain family, member 1A antibody; rasgef1a antibody; RGF1A_HUMAN antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q8N9B8

Immunogen:Fusion protein of Human RASGEF1A

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, IHC; ELISA:1:2000-1:5000, IHC:1:20-1:100

Background:RASGEF1A (RasGEF domain family, member 1A) is a 481 amino acid guanine-nucleotide exchange factor (GEF) for H-Ras, K-Ras, and N-Ras. RASGEF1A may also play a role in cell migration. RASFEG1A is highly expressed in spinal chord and brain and contains one N-terminal Ras-GEF domain and one Ras-GEF domain. The gene that encodes RASGEF1A maps to human chromosome 10, which contains over 800 genes and 135 million nucleotides, making up nearly 4.5% of the human genome. PTEN is an important tumor suppressor gene located on chromosome 10 and, when defective, causes a genetic predisposition to cancer development known as Cowden syndrome.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:RASGEF1A

Research Areas:Cancer;Signal transduction