RANBP2 Antibody - Cat. #: CSB-PA019311LA01HU

SKU: CSB-PA019311LA01HU

Size :50ug

Clone Number:

Aliases:358 kDa nucleoporin antibody; ANE1 antibody; E3 SUMO-protein ligase RanBP2 antibody; IIAE3 antibody; Nuclear pore complex protein Nup358 antibody; Nucleoporin 358 antibody; Nucleoporin Nup358 antibody; NUP358 antibody; p270 antibody; RAN binding protein 2 antibody; Ran-binding protein 2 antibody; RANBP2 antibody; RBP2_HUMAN antibody; Transformation related protein 2 antibody; TRP 1 antibody; TRP 2 antibody; TRP1 antibody; TRP2 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P49792

Immunogen:Recombinant Human E3 SUMO-protein ligase RanBP2 protein (2601-2802AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background:E3 SUMO-protein ligase which facilitates SUMO1 and SUMO2 conjugation by UBE2I. Involved in transport factor (Ran-GTP, karyopherin)-mediated protein import via the F-G repeat-containing domain which acts as a docking site for substrates. Binds single-stranded RNA (in vitro). May bind DNA. Component of the nuclear export pathway. Specific docking site for the nuclear export factor exportin-1. Sumoylates PML at \'Lys-490\' which is essential for the proper assembly of PML-NB.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Non-conjugated

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:RANBP2

Research Areas:Epigenetics and Nuclear Signaling; Cell biology; Signal transduction