Rabbit anti-human PTPRE Antibody - Cat. #: CSB-PA019052ESR2HU

SKU: CSB-PA019052ESR2HU

Size :50ul

Clone Number:

Aliases:DKFZp313F1310 antibody; FLJ57799 antibody; FLJ58245 antibody; HPTPE antibody; Protein tyrosine phosphatase epsilon antibody; Protein tyrosine phosphatase receptor type E antibody; Protein tyrosine phosphatase receptor type epsilon antibody; Protein tyrosine phosphatase receptor type epsilon polypeptide antibody; Protein-tyrosine phosphatase epsilon antibody; PTPE antibody; Ptpre antibody; PTPRE_HUMAN antibody; R PTP Epsilon antibody; R-PTP-epsilon antibody; Receptor-type tyrosine-protein phosphatase epsilon antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P23469

Immunogen:Recombinant Human Receptor-type tyrosine-protein phosphatase epsilon protein

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200

Background:Isoform 1 plays a critical role in signaling transduction pathways and phosphoprotein network topology in red blood cells. May play a role in osteoclast formation and function (By similarity).Isoform 2 acts as a negative regulator of insulin receptor (IR) signaling in skeletal muscle. Regulates insulin-induced tyrosine phosphorylation of insulin receptor (IR) and insulin receptor substrate 1 (IRS-1), phosphorylation of protein kinase B and glycogen synthase kinase-3 and insulin induced stimulation of glucose uptake.Isoform 1 and isoform 2 act as a negative regulator of FceRI-mediated signal transduction leading to cytokine production and degranulation, most likely by acting at the level of SYK to affect downstream events such as phosphorylation of SLP76 and LAT and mobilization of Ca2+.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen Affinity Purified

Conjugate:Non-conjugated

Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:PTPRE

Research Areas:Signal transduction