RAB23 Antibody - Cat. #: CSB-PA891960ESR2HU

SKU: CSB-PA891960ESR2HU

Size :50ul

Clone Number:

Aliases:DKFZp781H0695 antibody; HSPC137 antibody; MGC8900 antibody; Rab 23 antibody; RAB family small GTP binding protein RAB 23 antibody; Rab23 antibody; RAB23; member RAS oncogene family antibody; RAB23_HUMAN antibody; Ras related protein Rab 23 antibody; Ras-related protein Rab-23 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9ULC3

Immunogen:Recombinant Human Ras-related protein Rab-23 protein (1-237AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background:The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. Together with SUFU, prevents nuclear import of GLI1, and thereby inhibits GLI1 transcription factor activity. Regulates GLI1 in differentiating chondrocytes. Likewise, regulates GLI3 proteolytic processing and modulates GLI2 and GLI3 transcription factor activity. Plays a role in autophagic vacuole assembly, and mediates defense against pathogens, such as S.aureus, by promoting their capture by autophagosomes that then merge with lysosomes.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen Affinity Purified

Conjugate:Non-conjugated

Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:RAB23

Research Areas:Neuroscience; Signal transduction; Stem cells