Purified Anti-Mouse Ly6A/E Antibody[D7]

SKU: GBS-F1191A

Size:1mg

Storage:Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Flow Cytometry Antibodies

Abbreviation:Ly6A/E

Target Synonym:SCA;Ly-6A2/Ly-6E;Ly-6A.2/Ly-6E.1;SCA-1;TAP;Ly6;Ly6a

Research Areas:

Conjugation:Unconjugated

Host:Rat

Species reactivity:Mouse

Application:FCM

Usage:

Isotype:Rat IgG2a, κ

Clonality:Monoclonal

Clone NO.:D7

UNIProt ID:P05533

Background:Ly-6A/E, also known as Sca-1, is an 18 kD member of the Ly-6 multigene family. Ly6A/E is a glycosylphosphatidylinositol (GPI)-linked protein expressed on hematopoietic stem cells. In mice expressing the Ly-6.2 haplotype (e.g., AKR, C57BL, C57BR, DBA/2, SJL, SWR, and 129), Ly-6A/E is also expressed on peripheral B lymphocytes and thymic and peripheral T lymphocytes. Strains expressing the Ly-6.1 haplotype (e.g., BALB/c, CBA, C3H/He, DBA/1, and NZB) have low Ly-6A/E expression on resting peripheral lymphocytes. The expression of Ly-6A/E on lymphocytes is upregulated upon activation from both Ly6.1 and Ly6.2 haplotype mice. Ly-6A/E is thought to be involved in the regulation of both T and B cell responses.

Concentration: ≥ 1 mg/mL

Control catalog number:

Immunogen:Recombinant Mouse Ly6A/E protein

Buffer:Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.

Purification method:>98%, Protein A/G purified

Dilution:FCM 2 μg/mL(0.5×10⁶-1×10⁶ cells)

GeneID: