Purified Anti-Human CD7 Antibody[HIT7]

SKU: GBS-F1315A

Size:1mg

Storage:Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Flow Cytometry Antibodies

Abbreviation:CD7

Target Synonym:CD7;GP40;T-cell antigen CD7;T-cell leukemia antigen;T-cell surface antigen Leu-9;TP41

Research Areas:Costimulatory Molecules;Immunology

Conjugation:Unconjugated

Host:Mouse

Species reactivity:Human

Application:FCM

Usage:Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10⁶ cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

Isotype:Mouse IgG1, κ

Clonality:Monoclonal

Clone NO.:HIT7

UNIProt ID:P09564

Background:CD7 is a 40 kD type I transmembrane glycoprotein also known as gp40. It is a member of the immunoglobulin superfamily found on T cells, NK cells, thymocytes, hematopoietic progenitors, and monocytes (weakly). CD7 is also expressed on acute lymphocytic leukemia (ALL) and some acute myeloid leukemia (AML) cells. CD7 crosslinking induces a calcium flux in T lymphocytes, presumably as a result of cytoplasmic domain association with PI3-kinase. CD7 costimulation can induce cytokine secretion and modulate cellular adhesion.

Concentration:≥ 1 mg/mL

Control catalog number:

Immunogen:

Buffer:Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.

Purification method:

Dilution:FCM 2 μg/mL(0.5×10⁶-1×10⁶ cells)

GeneID:924