PTRH2 Antibody - Cat. #: CSB-PA698004

SKU: CSB-PA698004

Size :50ul

Clone Number:

Aliases:Bcl 2 inhibitor of transcription 1 antibody; Bcl-2 inhibitor of transcription 1 antibody; BIT 1 antibody; BIT1 antibody; CGI 147 antibody; CGI147 antibody; mitochondrial antibody; Peptidyl tRNA hydrolase 2 mitochondrial antibody; Peptidyl-tRNA hydrolase 2 antibody; PTH 2 antibody; PTH2 antibody; PTH2_HUMAN antibody; PTRH 2 antibody; PTRH2 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9Y3E5

Immunogen:Fusion protein of Human PTRH2

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, WB, IHC; ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:10-1:50

Background:PTRH2 (peptidyl-tRNA hydrolase 2), also known as BIT1 (Bcl-2 inhibitor of transcription 1), is a 179 amino acid mitochondrial protein. During apoptosis, PTRH2 is released from the mitochondia to the cytoplasm. Once in the cytoplasm, PTRH2 regulates the function of two transcriptional regulators, TLE5 and TLE1, thereby promoting caspase-independent cell death. It is also believed that the natural substrate for PTRH2 may be petidyl-tRNAs, which leave the ribosomes during protein synthesis.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:PTRH2

Research Areas:Epigenetics and Nuclear Signaling;Cancer;Cell biology;Metabolism