PTCH1 Antibody - Cat. #: CSB-PA623823LA01HU

SKU: CSB-PA623823LA01HU

Size :50ug

Clone Number:

Aliases:A230106A15Rik antibody; BCNS antibody; FLJ26746 antibody; FLJ42602 antibody; Holoprosencephaly 7 antibody; HPE7 antibody; mes antibody; NBCCS antibody; OTTHUMP00000021709 antibody; OTTHUMP00000021710 antibody; Patched antibody; Patched (Drosophila) homolog antibody; Patched 1 antibody; Patched homolog (Drosophila) antibody; Patched homolog 1 (Drosophila) antibody; Patched homolog 1 antibody; Patched protein homolog 1 antibody; Protein patched homolog 1 antibody; PTC antibody; PTC1 antibody; PTC1_HUMAN antibody; PTCH antibody; PTCH protein +12b antibody; PTCH protein +4' antibody; PTCH protein -10 antibody; PTCH protein antibody; ptch1 antibody; PTCH1 protein antibody; PTCH11 antibody; Ptch2 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q13635

Immunogen:Recombinant Human Protein patched homolog 1 protein (1180-1411AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200

Background:Acts as a receptor for sonic hedgehog (SHH), indian hedgehog (IHH) and desert hedgehog (DHH). Associates with the smoothened protein (SMO) to transduce the hedgehog\'s proteins signal. Seems to have a tumor suppressor function, as inactivation of this protein is probably a necessary, if not sufficient step for tumorigenesis.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Non-conjugated

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:PTCH1

Research Areas:Neuroscience; Cancer; Cell biology; Stem cells