PSENEN Antibody, HRP conjugated - Cat. #: CSB-PA878932OB01HU

SKU: CSB-PA878932OB01HU

Size :50ul

Clone Number:

Aliases:Gamma secretase subunit PEN 2 antibody; Gamma Secretase Subunit PEN2 antibody; Gamma-secretase subunit PEN-2 antibody; Hematopoietic stem/progenitor cells protein MDS033 antibody; MDS033 antibody; MSTP064 antibody; PEN 2 antibody; PEN2_HUMAN antibody; Presenilin Enhancer 2 antibody; Presenilin enhancer 2 homolog antibody; Presenilin enhancer protein 2 antibody; PSEN2 antibody; psenen antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9NZ42

Immunogen:Peptide sequence from Human Gamma-secretase subunit PEN-2 protein (39-57AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA

Background:Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein) (PubMed:12522139, PubMed:12763021, PubMed:12740439, PubMed:12679784, PubMed:24941111). The gamma-secretase complex plays a role in Notch and Wnt signaling cascades and regulation of downstream processes via its role in processing key regulatory proteins, and by regulating cytosolic CTNNB1 levels (Probable). PSENEN modulates both endoproteolysis of presenilin and gamma-secretase activity (PubMed:12522139, PubMed:12763021, PubMed:12740439, PubMed:12679784, PubMed:24941111).

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:HRP

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:PSENEN

Research Areas:Neuroscience