PRKDC Monoclonal Antibody

SKU: BT-MCA3152

Size:100μL

Background:The PRKDC gene encodes the catalytic subunit of a nuclear DNA-dependent serine/threonine protein kinase (DNA-PK). The second component is the autoimmune antigen Ku (MIM 152690), which is encoded by the G22P1 gene on chromosome 22q. On its own, the catalytic subunit of DNA-PK is inactive and relies on the G22P1 component to direct it to the DNA and trigger its kinase activity; PRKDC must be bound to DNA to express its catalytic properties.

Research_area:Epigenetics and Nuclear Signaling

Target_protein:PRKDC

applications:IHC, ICC

Reactivity:Human

Clonality:Monoclonal

Clone ID:3H6

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:PRKDC

Immunogen:Purified recombinant fragment of human PRKDC expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Ascitic fluid containing 0.03% sodium azide.

Concentration:

Molecular weight(Da):46.9kDa

UniProt accession:P78527

Synonyms:HYRC, p350, DNAPK, DNPK1, HYRC1, XRCC7, DNA-PKcs, PRKDC

GeneID:5591