PPP1R16B Antibody, FITC conjugated - Cat. #: CSB-PA842762LC01HU

SKU: CSB-PA842762LC01HU

Size :50ug

Clone Number:

Aliases:ANKRD4 antibody; Ankyrin repeat domain containing protein 4 antibody; ankyrin repeat domain protein 4 antibody; Ankyrin repeat domain-containing protein 4 antibody; CAAX box protein TIMAP antibody; hTIMAP antibody; KIAA0823 antibody; PP16B_HUMAN antibody; PPP1R16B antibody; Protein phosphatase 1 regulatory inhibitor subunit 16B antibody; protein phosphatase 1, regulatory (inhibitor) subunit 16B antibody; TGF beta inhibited membrane associated protein antibody; TGF-beta-inhibited membrane-associated protein antibody; TIMAP antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q96T49

Immunogen:Recombinant Human Protein phosphatase 1 regulatory inhibitor subunit 16B protein (101-400AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:

Background:Regulator of protein phosphatase 1 (PP1) that acts as a positive regulator of pulmonary endothelial cell (EC) barrier function. Involved in PKA-mediated moesin dephosphorylation which is important in EC barrier protection against thrombin stimulation. Promotes the interaction of PPP1CA with RPSA/LAMR1 and in turn facilitates the dephosphorylation of RPSA/LAMR1. Involved in the regulation of endothelial cell filopodia extension. May be a downstream target for TGF-beta1 signaling cascade in endothelial cells.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:FITC

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:PPP1R16B

Research Areas:Signal transduction