PP2B-A alpha Rabbit Polyclonal Antibody

SKU: BT-AP04227

Size:100μL

Background:Catalytic activity:A phosphoprotein + H(2)O = a protein + phosphate.|cofactor:Binds 1 Fe(3+) ion per subunit.|cofactor:Binds 1 zinc ion per subunit.|Calcium-dependent| calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin. Dephosphorylates HSPB1 and SSH1.|online information:Calcineurin entry|Belongs to the PPP phosphatase family.|Belongs to the PPP phosphatase family. PP-2B subfamily.|subcellular location:Colocalizes with ACTN1 and MYOZ2 at the Z line in heart and skeletal muscle.|subunit:Composed of two components (A and B)| the A component is the catalytic subunit and the B component confers calcium sensitivity. Interacts with TORC2/CRTC2| MYOZ1| MYOZ2 and MYOZ3.|

Research_area:Immunology; Signal transduction

Target_protein:PPP3CA

applications:WB, ELISA

Reactivity:Human, Mouse, Rat

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:PP2B-Aalpha

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):57310

UniProt accession:Human: Q08209; Mouse: P63328; Rat: P63329

Synonyms:PP2B-Aα; Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform; EC 3.1.3.16; CAM-PRP catalytic subunit; Calmodulin-dependent calcineurin A subunit alpha isoform

GeneID:Human: 5530; Mouse: 19055; Rat: 24674