PNKP Polyclonal Antibody

SKU: BT-AP13205

Size:100μL

Background:This locus represents a gene involved in DNA repair. In response to ionizing radiation or oxidative damage, the protein encoded by this locus catalyzes 5' phosphorylation and 3' dephosphorylation of nucleic acids. Mutations at this locus have been associated with microcephaly, seizures, and developmental delay.

Research_area:Epigenetics and nuclear signaling

Target_protein:PNKP

applications:WB, ELISA

Reactivity:Human, Rat, Mouse

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:Bifunctional polynucleotide phosphatase/kinase

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):

UniProt accession:Human: Q96T60; Mouse: Q9JLV6

Synonyms:Bifunctional polynucleotide phosphatase/kinase ;DNA 5'-kinase/3'-phosphatase;Polynucleotide kinase-3'-phosphatase [Includes: Polynucleotide 3'-phosphatase ;EC 3.1.3.32;2';3'-polynucleotidase; P

GeneID:Human: 11284