PLCG2 (Ab-1217) Antibody - Cat. #: CSB-PA834542

SKU: CSB-PA834542

Size :100ul

Clone Number:

Aliases:1 phosphatidylinositol 4 5 bisphosphate phosphodiesterase gamma 2 antibody; 1-phosphatidylinositol-4 antibody; 5-bisphosphate phosphodiesterase gamma-2 antibody; EC 3.1.4.11 antibody; Phosphoinositide phospholipase C antibody; Phosphoinositide phospholipase C-gamma-2 antibody; Phospholipase C gamma 2 antibody; Phospholipase C, gamma 2 (phosphatidylinositol specific) antibody; Phospholipase C-gamma-2 antibody; Phospholipase C-IV antibody; PLC 2 antibody; PLC gamma 2 antibody; PLC IV antibody; PLC-gamma-2 antibody; PLC-IV antibody; Plcg2 antibody; PLCG2_HUMAN antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P16885

Immunogen:Peptide sequence around aa.1215~1219 (F-L-Y-D-T) derived from Human PLCg2.

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, IHC, IF; IHC:1:50-1:100, IF:1:100-1:200

Background:The production of the second messenger molecules diacylglycerol. (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. It is a crucial enzyme in transmembrane signaling.

Singer, W. D. et al. (1997) Annu. Rev. Biochem. 66, 475-509.
Smrcka, A. V. et al. (1991) Science 251, 804-807.
Yue, C. et al. (2000) J. Biol. Chem. 275, 30220-30225.
Watanabe, D. et al. (2001) J. Biol. Chem. 276, 38595-38601.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Conjugate:Non-conjugated

Buffer:Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:PLCG2

Research Areas:Cancer?Cardiovascular;Metabolism;Signal transduction