PLCG1 (Ab-771) Antibody - Cat. #: CSB-PA161792

SKU: CSB-PA161792

Size :100ul

Clone Number:

Aliases:1 phosphatidyl D myo inositol 4 5 bisphosphate antibody; 1 phosphatidylinositol 4 5 bisphosphate phosphodiesterase gamma 1 antibody; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 antibody; Inositoltrisphosphohydrolase antibody; Monophosphatidylinositol phosphodiesterase antibody; NCKAP3 antibody; Phosphatidylinositol phospholipase C antibody; Phosphoinositidase C antibody; Phosphoinositide phospholipase C antibody; Phosphoinositide phospholipase C-gamma-1 antibody; Phospholipase C 148 antibody; Phospholipase C gamma 1 antibody; Phospholipase C-gamma-1 antibody; Phospholipase C-II antibody; PLC gamma 1 antibody; PLC II antibody; PLC-148 antibody; PLC-gamma-1 antibody; PLC-II antibody; PLC1 antibody; PLC148 antibody; Plcg1 antibody; PLCG1_HUMAN antibody; PLCgamma1 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P19174

Immunogen:Synthesized non-phosphopeptide derived from Human PLCG1 around the phosphorylation site of tyrosine 771 (P-D-Y-G-A).

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, WB, IHC; WB:1:500-1:3000, IHC:1:50-1:100

Background:Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. Becomes activated in response to ligand-mediated activation of receptor-type tyrosine kinases, such as PDGFRA, PDGFRB, FGFR1, FGFR2, FGFR3 and FGFR4. Plays a role in actin reorganization and cell migration.

Denis Tvorogov, J. Cell Sci., Feb 2005; 118: 601 - 610.
Brenda J. Irvin, Mol. Cell. Biol., Dec 2000; 20: 9149 - 9161.
Benoit Poulin, J. Biol. Chem., Feb 2000; 275: 6411.
Ichiro Nakamura, J. Cell Biol., Jan 2001; 152: 361.

Clonality:Polyclonal

Isotype:IgG

Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:PLCG1

Research Areas:Cancer?Cardiovascular;Metabolism;Signal transduction