PIM3 Antibody, FITC conjugated - Cat. #: CSB-PA771444LC01HU

SKU: CSB-PA771444LC01HU

Size :50ug

Clone Number:

Aliases:Kid 1 antibody; Kid1 antibody; Kinase induced by depolarization antibody; ONCOGENE PIM3 antibody; PIM 3 antibody; Pim 3 oncogene antibody; Pim-3 proto-oncogene; serine/threonine kinase antibody; PIM3 antibody; Pim3 oncogene antibody; PIM3_HUMAN antibody; Protein kinase Kid 1 antibody; Protein kinase Kid1 antibody; Serine/threonine kinase Pim 3 antibody; Serine/threonine kinase Pim3 antibody; Serine/threonine protein kinase Pim 3 antibody; Serine/threonine protein kinase Pim3 antibody; Serine/threonine-protein kinase Pim-3 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q86V86

Immunogen:Recombinant Human Serine/threonine-protein kinase pim-3 protein (278-326AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:

Background:Proto-oncogene with serine/threonine kinase activity that can prevent apoptosis, promote cell survival and protein translation. May contribute to tumorigenesis through: the delivery of survival signaling through phosphorylation of BAD which induces release of the anti-apoptotic protein Bcl-X(L), the regulation of cell cycle progression, protein synthesis and by regulation of MYC transcriptional activity. Additionally to this role on tumorigenesis, can also negatively regulate insulin secretion by inhibiting the activation of MAPK1/3 (ERK1/2), through SOCS6. Involved also in the control of energy metabolism and regulation of AMPK activity in modulating MYC and PPARGC1A protein levels and cell growth.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:FITC

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:PIM3

Research Areas:Epigenetics and Nuclear Signaling; Cancer; Signal transduction