Phospho-YWHAZ (Ser58) Antibody - Cat. #: CSB-PA887076

SKU: CSB-PA887076

Size :100ul

Clone Number:

Aliases:14 3 3 delta antibody; 14 3 3 protein zeta/delta antibody; 14 3 3 protein/cytosolic phospholipase A2 antibody; 14 3 3 zeta antibody; 14-3-3 protein zeta/delta antibody; 1433Z_HUMAN antibody; Epididymis luminal protein 4 antibody; Epididymis secretory protein Li 3 antibody; HEL S 3 antibody; HEL4 antibody; KCIP-1 antibody; KCIP1 antibody; MGC111427 antibody; MGC126532 antibody; MGC138156 antibody; Phospholipase A2 antibody; Protein kinase C inhibitor protein 1 antibody; Tyrosine 3 monooxygenase/tryptophan 5 monooxygenase activation protein; delta polypeptide antibody; Tyrosine 3 monooxygenase/tryptophan 5 monooxygenase activation protein; zeta antibody; Tyrosine 3 monooxygenase/tryptophan 5 monooxygenase activation protein; zeta polypeptide antibody; Tyrosine 3/tryptophan 5 monooxygenase activation protein; zeta polypeptide antibody; YWHAD antibody; YWHAZ antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P63104

Immunogen:Peptide sequence around phosphorylation site of serine 58 (R-S-S(p)-W-R) derived from Human 14-3-3 zeta.

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, WB, IHC, IF; WB:1:500-1:1000, IHC:1:50-1:100, IF:1:100-1:200

Background:This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Several transcript variants that differ in the 5' UTR but that encode the same protein have been identified for this gene.

Gu YM, et al. (2006) FEBS Lett ; 580(1): 305-310
Powell DW, et al. (2003) Mol Cell Biol; 23(15): 5376-5387
Mackintosh C. (2004) Biochem J; 381(Pt 2): 329-342.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Conjugate:Non-conjugated

Buffer:Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:YWHAZ

Research Areas:Neuroscience;Cell biology;Tags & Cell Markers;Signal transduction