Phospho-TGFBR2 (Ser225/250) Antibody - Cat. #: CSB-PA911102

SKU: CSB-PA911102

Size :100ul

Clone Number:

Aliases:AAT3 antibody; FAA3 antibody; LDS1B antibody; LDS2 antibody; LDS2B antibody; MFS2 antibody; RIIC antibody; TAAD2 antibody; TbetaR II antibody; TbetaR-II antibody; TGF beta receptor type 2 antibody; TGF beta receptor type II antibody; TGF beta receptor type IIB antibody; TGF beta type II receptor antibody; TGF-beta receptor type II antibody; TGF-beta receptor type-2 antibody; TGF-beta type II receptor antibody; TGF-beta-R2 antibody; TGFB R2 antibody; TGFbeta - RII antibody; TGFbeta RII antibody; Tgfbr2 antibody; TGFR-2 antibody; TGFR2_HUMAN antibody; Transforming growth factor beta receptor II antibody; Transforming growth factor beta receptor type II antibody; Transforming growth factor beta receptor type IIC antibody; Transforming growth factor, beta receptor II (70/80kDa) antibody; transforming growth factor, beta receptor II alpha antibody; transforming growth factor, beta receptor II beta antibody; transforming growth factor, beta receptor II delta antibody; transforming growth factor, beta receptor II epsilon antibody; transforming growth factor, beta receptor II gamma antibody; Transforming growth factor-beta receptor type II antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P37173

Immunogen:Peptide sequence around phosphorylation site of Serine 225/250(D-R-S(p)-D-I) derived from Human TGF ? Receptor II.

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, IHC; IHC:1:50-1:100

Background:Transmembrane serine/threonine kinase forming with the TGF-beta type I serine/threonine kinase receptor, TGFBR1, the non-promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinogenesis. RC Tripathi, Invest. Ophthalmol. Vis. Sci., Jan 1993; 34: 260. N Chegini, Endocrinology, Jul 1994; 135: 439. GW Mulheron, Endocrinology, Dec 1992; 131: 2609

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:TGFBR2

Research Areas:Signal transduction?Stem cells